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This statement is based on the following facts 1 In areas in which penicillin resistance has been present for many years, the minimum inhibitory concentration of antibiotic MIC inhibiting 90 of bacterial strains MIC90 is still 1 mg L 1, and MIC of 4 mg L 1 are extremely rare 40, 55, 56; 2 With high dose penicillin or amoxicillin, adequate concentrations at the site of infection are achieved even when treating highly resistant MIC 4 mg L 1 pneumococci 57; 3 To date, studies of pneumonia treated with penicillins or other b lactams, adjusted for underlying factors and severity of illness, have shown a similar and favourable outcome in patients in whom the infection was caused by penicillin resistant strains to that in infections caused by penicillin sensitive strains 40, 55, 58 61; 4 Among pneumococci with decreased susceptibility to penicillin MIC 0 cialis 5 mg best price usa |
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